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A DESeqResults object testing the effect of dexamethasone on smooth muscle cells

Format

A DESeqResults object, generated in the DESeq2 framework

Details

This DESeqResults object on the data from the airway package has been created comparing dexamethasone treated vs untreated samples, accounting for the different cell lines included.

Details on how this object has been created are included in the create_carnation_data.R script, included in the scripts folder of the Carnation package.

References

Himes BE, Jiang X, Wagner P, Hu R, Wang Q, Klanderman B, Whitaker RM, Duan Q, Lasky-Su J, Nikolos C, Jester W, Johnson M, Panettieri R Jr, Tantisira KG, Weiss ST, Lu Q. “RNA-Seq Transcriptome Profiling Identifies CRISPLD2 as a Glucocorticoid Responsive Gene that Modulates Cytokine Function in Airway Smooth Muscle Cells.” PLoS One. 2014 Jun 13;9(6):e99625. PMID: 24926665. GEO: GSE52778